The Hornets have reverted back to their familiar 3-5-2 formation, but there is no place for striker Odion Ighalo, who is fit again after a hamstring injury.
Fulham have made two changes to their side as Lasse Vigan Christensen and Scott Parker miss out.
Watford: Gomes; Cathcart, Angella, Hoban; Motta, Abdi, Watson, Guedioura, Pudil; Deeney, Vydra.
Subs: Bond, Paredes, Anya, Layun, Tozser, Forestieri, Ighalo.
Fulham: Bettinelli, Richards, Hutchinson, Bodurov, Stafylidis, Tunnicliffe, Fofana, Kavanagh, Ruiz, Woodrow, McCormack.
Subs: Kiraly, Hoogland, Amorebieta, Kačaniklić, Rodallega, Smith, Dembélé.