The Cottagers' starting XI shows four changes from the team that began their last Premier League outing, which was a 2-1 win at West Brom.
Schwarzer returns in place of David Stockdale, while Kieran Richardson, Damien Duff and Mladen Petric come in for Matthew Briggs, Ashkan Dejagah and Steven Sidwell, who has a slight problem with his hamstring.
Fulham: Schwarzer, Riether, Hangeland, Hughes, Richardson, Duff, Ruiz, Karagounis, Kacaniklic, Berbatov, Petric
Subs: Stockdale, Riise, Senderos, Baird, Kasami, Rodallega, Dejagah
Wigan: Al-Habsi, Boyce, Caldwell, Ramis, Figueroa, McCarthy, Jones, McArthur, Maloney, Beausejour, Di Santo
Subs: Pollitt, Stam, Golobart, Gomez, McManaman, Boselli, Henriquez