The home side will be hoping that Mark Little will be able to shake off a knock that he picked up in their last game against Watford.
They will also be hoping to continue the recent form that has seen them escape the relegation zone, beating two of the league's top three in the process.
Brighton, meanwhile, have very different ambitions. Gus Poyet's men are also in good form and will want to consolidate their playoff place in the final four games.
Peterborough United: WDDWWD
Brighton & Hove Albion: WDDDWL
Possible starting lineups
Peterborough United: Olejnik; Alcock, Zakuani, Brisley, Swanson; McCann, Rowe, Ferdinand, Knight-Percival, Tomlin; Gayle
Brighton & Hove Albion: Ankergren; Greer, Calderon, Upson, Bridge; Crofts, Orlandi, Hammond, Lopez, Bridcutt; Ulloa
Sports Mole says: 1-1