Liga MX 2020-21 Head-to-Head
Top Six
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Club Leon | 13 | 5 | 6 | 2 | 16 | 14 | 2 | 21 |
| 2 | CD GuadalajaraGuadalajara | 15 | 5 | 5 | 5 | 16 | 17 | -1 | 20 |
| 3 | Club AmericaAmerica | 14 | 6 | 1 | 7 | 21 | 21 | 0 | 19 |
| 4 | PachucaPachuca | 13 | 4 | 5 | 4 | 15 | 14 | 1 | 17 |
| 5 | MonterreyMonterrey | 10 | 4 | 2 | 4 | 13 | 12 | 1 | 14 |
| 6 | TolucaToluca | 11 | 2 | 5 | 4 | 13 | 16 | -3 | 11 |
Bottom Six
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | PumasPumas | 10 | 5 | 5 | 0 | 13 | 4 | 9 | 20 |
| 2 | Santos LagunaSantos Laguna | 10 | 5 | 2 | 3 | 16 | 9 | 7 | 17 |
| 3 | MazatlanMazatlan | 10 | 4 | 2 | 4 | 10 | 15 | -5 | 14 |
| 4 | NecaxaNecaxa | 10 | 4 | 1 | 5 | 10 | 11 | -1 | 13 |
| 5 | Juarez | 10 | 2 | 4 | 4 | 10 | 12 | -2 | 10 |
| 6 | Club TijuanaTijuana | 10 | 2 | 2 | 6 | 5 | 13 | -8 | 8 |
