The 20-year-old comes in for Sean Rigg as the U's make just one change to the side that beat Morecambe 3-0 on Saturday.
Oxford: Clarke, Hunt, Raynes, Mullins, Newey, Williams, Hall, Rose, Ruffels, Kitson, Constable
Subs: Davies, Marsh, Crocombe, Long, Lynn, Bevans, O'Dowda
Newport: Pidgeley, Yakubu, Oshilaja, Worley, Chapman, Minshull, Willmott, Washington, Jackson, Crow, Jolley
Subs: Hughes, Jones, Naylor, Pipe, Sandell, Flynn, Barker