© PA Photos
The former England international received his marching order following a challenge with Jordi Gomez, who was caught on the head by Zamora's wayward boot in the 21st minute.
Prior to that QPR had began the clash brightly and went close to breaking the deadlock in the 15th minute. Junior Hoilett chested the ball into the path of Loic Remy, who unleashed a powerful strike from 25 yards. It beat Joel Robles in the Wigan goal, but the ball rebounded to safety off the post.
Following the dismissal of Zamora, Wigan saw more of the ball but were unable to turn their domination into goals.
Callum McManaman went closest, but he curled a shot from the edge of the area just over the crossbar.