Abel Hernandez starts up front at the expense of the benched Evandro, as the Portuguese manager looks to extend his unbeaten home record at the KCOM and increase the gap between the Tigers and the bottom three.
Dieumerci Mbokani, who has sat out the last two games with a hamstring problem, is available to be called upon from the bench.
David Moyes, who has confirmed that he will retain the helm at the Stadium of Light in the second tier next season, make three changes from the side that suffered the relegation-ensuring defeat to Bournemouth a week ago.
Victor Anichebe, who has failed to score since his brace against this opposition in November, starts alongside Fabio Borini and Jermain Defoe up front, while Sebastian Larsson returns from a three-match suspension to take a place on the bench.
Hull City: Jakupovic; Elmohamady, Robertson, Maguire, Ranocchia; N'Diaye, Clucas, Markovic, Grosicki; Niasse, Hernandez
Subs: Marshall, Dawson, Huddlestone, Maloney, Henriksen, Evandro, Mbokani
Sunderland: Pickford; Jones, Manquillo, O'Shea, Kone; Denayer, Ndong, Honeyman; Borini, Anichebe, Defoe
Subs: Mannone, Djilobodji, Khazri, Love, Gooch, Rodwell, Larsson
Follow all the action from this afternoon's game courtesy of Sports Mole's blow-by-blow updates.