The hosts have not won since the first day of the season, but have drawn their last three including the 1-1 away to Livorno on Wednesday.
Inter, who beat Sassuolo 7-0 a week ago, left it late to win against Fiorentina in the week and are currently second in the table.
Possible starting lineups
Cagliari: Agazzi; Astori, Rossettini, Perico, Nainggolan; Pinilla, Avelar, Conti, Dessena; Nene, Ibarbo
Inter: Handanovic; Ranocchia, Jonathan, Nagatomo, Jesus; Campagnaro, Guarin, Cambiasso, Alvarez; Taider; Palacio
Sports Mole says: 1-2