A draw with the Addicks will be enough to ensure that the league leaders will be playing in the top flight next season.
The Welsh side have reported no new injury problems following their 3-0 win over Nottingham Forest on Saturday.
Meanwhile, Charlton still have a chance to claim a playoff place, having lost just one of their last six matches.
The visitors will head to the Cardiff City Stadium full of confidence, having thrashed Barnsley 6-0 at Oakwell yesterday.
Cardiff: Marshall, McNaughton, Taylor, Turner, Barnett, Noone, Gunnarsson, Mutch, Smith, Gestede, Bellamy
Charlton: Hamer, Morrison, Wiggins, Solly, Dervite, Hughes, Gower, Pritchard, Harriotts, Obika, Fuller
Sports Mole says: 2-2