Sandro, 20, makes just his seventh league start for Barcelona, as they start both Neymar and Suarez in what is potentially a full-strength strike-force.
The Catalan side have won their two previous league games against Eibar without conceding a goal, but they have lost twice in their last four games in La Liga.
Barcelona: Bravo; Alves, Pique, Bartra, Alba; Rakitic, Busquets, Mascherano; Sandro, Suárez, Neymar
Subs: Ter Stegen, Douglas, Vermaelen, Gumbau, Mathieu, El Haddadi, Correia
Eibar: Riesgo; Capa, Dos Santos, Pantic, Junca; Escalante, Dani Garcia; Verdi, Keko, Inui; Borja Baston
Subs: Irureta, Ekiza, Castellano, Pascual, Berjon, Hajrovic, Enrich