Forest have began the season in fine style, putting together four wins and a draw to earn a place at the top of the Championship table.
McClaren also has doubts over winger Jamie Ward, who suffered a muscle injury during Northern Ireland's win in Hungary on Sunday.
The Rams are currently in seventh place after picking up eight points from their opening five league games.
Nottingham Forest: DWWWW
Derby County: DLWWD
Possible starting lineups
Nottingham Forest: Darlow; Hunt, Mancienne, Hobbs, Lichaj; Burke, Cohen, Antonio, Reid, Lansbury; Assombalonga
Derby County: Grant; Christie, Forsyth, Keogh, Buxton; Eustace, Hughes, Bryson, Dawkins, Russell; Martin
Sports Mole says: 2-1