League Two 2021-22 Head-to-Head
Top Six
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| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Northampton TownNorthampton | 10 | 6 | 3 | 1 | 18 | 8 | 10 | 21 |
| 2 | Carlisle UnitedCarlisle | 10 | 6 | 1 | 3 | 13 | 11 | 2 | 19 |
| 3 | Bradford CityBradford | 10 | 4 | 3 | 3 | 11 | 9 | 2 | 15 |
| 4 | Salford City | 10 | 4 | 2 | 4 | 13 | 13 | 0 | 14 |
| 5 | Leyton Orient | 10 | 1 | 5 | 4 | 9 | 13 | -4 | 8 |
| 6 | Stevenage | 10 | 1 | 2 | 7 | 9 | 19 | -10 | 5 |
Bottom Six
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| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Port Vale | 10 | 6 | 2 | 2 | 14 | 10 | 4 | 20 |
| 2 | Exeter CityExeter | 10 | 5 | 4 | 1 | 15 | 4 | 11 | 19 |
| 3 | Forest Green RoversForest Green | 10 | 4 | 5 | 1 | 13 | 8 | 5 | 17 |
| 4 | Bristol Rovers | 10 | 4 | 2 | 4 | 18 | 14 | 4 | 14 |
| 5 | Oldham AthleticOldham | 10 | 3 | 1 | 6 | 15 | 21 | -6 | 10 |
| 6 | Scunthorpe UnitedScunthorpe | 10 | 1 | 0 | 9 | 5 | 23 | -18 | 3 |
Midlands Teams
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Northampton TownNorthampton | 6 | 3 | 2 | 1 | 5 | 2 | 3 | 11 |
| 2 | Walsall | 6 | 3 | 1 | 2 | 7 | 5 | 2 | 10 |
| 3 | Mansfield TownMansfield | 6 | 2 | 1 | 3 | 6 | 9 | -3 | 7 |
| 4 | Port Vale | 6 | 1 | 2 | 3 | 4 | 6 | -2 | 5 |
North-West Teams
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Tranmere RoversTranmere | 6 | 4 | 1 | 1 | 8 | 3 | 5 | 13 |
| 2 | Carlisle UnitedCarlisle | 6 | 2 | 2 | 2 | 6 | 6 | 0 | 8 |
| 3 | Rochdale | 6 | 2 | 1 | 3 | 3 | 5 | -2 | 7 |
| 4 | Oldham AthleticOldham | 6 | 1 | 2 | 3 | 2 | 5 | -3 | 5 |
