The Napoli chief will be keen to see an improvement from his team after they fell to a 1-0 defeat away at Parma last weekend.
Lazio have work to if they wish to earn a place in next season's Europa League, with five points separating the teams placed between fifth and 11th.
The Rome-based club, who are seventh in the standings, have won their last two matches but they will need to improve on their poor away form if they are to pick up a result in Naples.
Possible starting lineups
Napoli: Pepe Reina; Albiol, Henrique, Fernandez, Ghoulam; Inler, Hamsik, Jorginho; Callejon, Insigne, Higuain
Lazio: Berisha; Biava, Konko, Radu, Cana; Mauri, Candreva, Lulic; Onazi, Helder Postiga, Keita
Sports Mole says: 2-1