The Bhoys entertain the Spanish champions at Celtic Park, and the Northern Irishman has singled out his Greek forward as key to getting a positive result.
"He is hugely influential at times in these European games," Lennon told reporters ahead of the game.
"He enjoys the arena, he enjoys the challenge that these games bring. I hope that he hasn't peaked too early because I feel that to get something out of the game I need Samaras to have a big game.
"In the Camp Nou, before he went off injured, he was causing Barcelona lots of problems and I am hoping for more of the same tonight."
You can catch live Sports Mole's commentary of this evening's game here.