Neville, whose side lost both local derbies with Liverpool in the Premier League this season, admits that he and his teammates must focus on themselves in order to avoid another defeat to the Reds.
"Liverpool have beaten us twice this season," he told the club's official website.
"We've just got to make sure that we concentrate on ourselves, on the confidence and belief we've been building over these last three or four months.
"Liverpool have won the Carling Cup and their attention has turned to the FA Cup now. I think it's going to be a tight game and small details could decide it."
Kenny Dalglish's side beat the Toffees 3-0 in the Merseyside derby last month.