Queens Park Rangers and Tottenham Hotspur both make a host of changes to the teams that they used for the FA Cup last weekend.
Jermaine Defoe starts up front for Spurs alongside Emmanuel Adebayor, who is playing his last match for the club before leaving for the Africa Cup of Nations.
Gareth Bale is back in the starting lineup for Tottenham having served a one-match suspension in their last Premier League game.
Park Ji-Sung has recovered from a leg injury and is back for QPR.
Adel Taarabt will be QPR's lone striker, with Jamie Mackie playing off the front of the midfield.
QPR: Cesar, Hill, Onuoha, Nelsen, Da Silva, Mbia, Park, Derry, Taarabt, Wright-Phillips, Mackie
Tottenham: Lloris, Walker, Vertonghen, Dawson, Naughton, Sandro, Dembele, Lennon, Bale, Adebayor, Defoe
