Gerrard has revealed that he is "excited" about the landmark occasion, but is confident that he can go on to achieve more while representing his country, targeting qualification for the 2014 World Cup as the next milestone.
"I'm excited. I'm slightly nervous, which I haven't been for quite a while in an England shirt, maybe because there is a bit more attention on me getting to the milestone," he said.
"It's very exciting and I can't wait for the game to start. My England journey has been full of ups and downs, probably the same as a lot of other England players, but I feel like there's a few more chapters to write as well.
"I don't feel as if I am coming to the end. I'm really happy where I am at the moment and really happy with my form in an England shirt. I'm certainly looking forward to helping this team qualify for the World Cup."