Today's previews and predictions include Coventry City hosting Preston North End and Charlton Athletic's trip to second-placed Middlesbrough.
Birmingham City vs. Queens Park Rangers (Wednesday, 7.45pm)
We say: Birmingham City 2-1 Queens Park Rangers
Despite their severe dip in form of late, Birmingham are usually strong at St Andrew's and should be confident of enjoying a productive Wednesday night.
The R's are plagued with injuries at the moment and could sink further into midtable mediocrity with a defeat in the Second City.
Middlesbrough vs. Charlton Athletic (Wednesday, 7.45pm)
We say: Middlesbrough 3-0 Charlton Athletic
With Charlton having eased the pressure on themselves, they can afford to play with more freedom on their trip to the Riverside Stadium. However, we cannot ignore Boro's ruthlessness in the final third of late, leading us to predict a convincing home triumph.
Norwich City vs. Sheffield United (Wednesday, 7.45pm)
We say: Norwich City 2-1 Sheffield United
While Norwich City's FA Cup tie on Sunday may have knocked an already thin squad, given their extensive fitness concerns, the Canaries have been formidable in the Championship in recent months.
We fancy them to overcome a Sheffield United side facing a tough midweek trip on the back of a harmful draw at the weekend which may have cost them any realistic hopes of crashing the top six in the run-in.
Oxford United vs Blackburn Rovers (Wednesday, 7.45pm)
We say: Oxford United 2-1 Blackburn Rovers
While Blackburn sit in a far more comfortable position than their hosts, we cannot ignore that Oxford are the only team in the bottom seven to win their last two matches. With home advantage in their favour, Oxford could deliver another three points to move outside of the relegation zone, if other results go their way.
West Bromwich Albion vs. Southampton (Wednesday, 7.45pm)
We say: West Bromwich Albion 1-2 Southampton
Winless at The Hawthorns since December 29, West Brom are facing another difficult Black Country assignment against Southampton on Wednesday.
After beating Premier League outfit Fulham on their own patch, the Saints will be confident of extending their winning streak to four games in the West Midlands.
Coventry City vs. Preston North End (Wednesday, 8pm)
We say: Coventry City 2-0 Preston North End
Losing just one of their 17 Championship home matches so far in 2025-26, league leaders Coventry are the clear favourites for success on Wednesday night.
Preston's campaign is in the process of petering out after a string of poor results, with another disappointing match highly probable in the East Midlands.