Wednesday's Premier League predictions including Aston Villa vs. Manchester City

Spurs vs. Southampton (Wednesday, 6.00pm)

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Amid fury and condemnation from supporters over their involvement in the European Super League, Tottenham Hotspur begin life after Jose Mourinho when they welcome Southampton to North London in Wednesday's Premier League clash.

The hosts could only take a point from a 2-2 draw with Everton on Friday evening, whereas Southampton's FA Cup journey ended at the hands of Leicester City in the semi-finals.

We say: Tottenham Hotspur 2-1 Southampton

An immediate case of new manager bounce would have Spurs supporters dreaming of cup success under fresh management, but Mason must focus on the task at hand against Southampton first and foremost.

However, the Saints realistically only have pride to play for and travel to the capital with a dire away record, so we expect Spurs to begin the post-Mourinho era in perfect fashion with all three points.

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> How Southampton could line up against Tottenham

> How Tottenham could line up against Southampton

Aston Villa vs. Man City (Wednesday, 8.15pm)

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Aston Villa host Manchester City in the Premier League on Wednesday, with the Citizens requiring 11 more points to be assured of winning their third league title in the last four seasons under Pep Guardiola.

The Villans, meanwhile, can move back into the top half of the table by gaining a positive result.

We say: Aston Villa 0-2 Manchester City

Without Grealish, it is difficult to envisage Villa laying a glove on City, who will be highly motivated to bounce back after recent defeats to Leeds and Chelsea.

A win would go a long way to securing yet another league title for the club, and we expect City to edge a tight encounter on Wednesday.

> Click here to read our full preview for this match

> How Manchester City could line up against Aston Villa

> How Aston Villa could line up against Manchester City

> Man City injury, suspension list vs. Villa