Man City vs. Atletico (Tuesday, 8.00pm)
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Having already seen off one Manchester-based outfit this season, Atletico Madrid travel to the Etihad to face Manchester City in the first leg of their Champions League quarter-final on Tuesday night.
Pep Guardiola's side made it past Sporting Lisbon 5-0 on aggregate in the last 16, while the La Liga champions edged past the Red Devils 2-1 to make it to the quarters.
We say: Manchester City 1-1 Atletico Madrid
The distraction of Liverpool's visit to the Etihad in a week's time cannot creep into the minds of Man City's XI here, but another mammoth encounter with a somewhat depleted defence is not a cause for optimism.
Simeone's Atletico have been nothing if not resilient when at their best - Man United found that out well enough - and with Simeone having almost all of his big-hitters available, we can envisage the in-form Colchoneros holding Guardiola's men to a score draw before the return leg in the Spanish capital.
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> How Atletico Madrid could line up against Man City
> How Man City could line up against Atletico
> Man City injury, suspension list vs. Atletico Madrid
Benfica vs. Liverpool (Tuesday, 8.00pm)
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Having been handed what some fans may feel is the most favourable Champions League draw, Liverpool travel to the Estadio da Luz for the first leg of their quarter-final with Benfica on Tuesday night.
The Reds dumped Inter Milan out of the tournament 2-1 on aggregate to make it this far, while Nelson Verissimo's side claimed a 3-2 win over Ajax over two legs.
We say: Benfica 1-2 Liverpool
A Nunez-inspired Benfica ought to be well up for this colossal European tie in front of their own fans, but their veteran backline of Vertonghen and Otamendi could prove easy pickings for Liverpool's rampant attackers.
Klopp admitted that his side did not create enough against Watford as the players begin to gel following the international break, and this may be a closer affair than the Reds would like, but they should still take advantage of Benfica's recent defensive lapses to claim a first-leg advantage.
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> How Benfica could line up against Liverpool