Welsh Premier League 2021-22 Head-to-Head
Top Six
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | The New SaintsNew Saints | 15 | 11 | 3 | 1 | 37 | 11 | 26 | 36 |
| 2 | Newtown AFCNewtown | 16 | 6 | 4 | 6 | 18 | 17 | 1 | 22 |
| 3 | Connah's Quay NomadsConnah's Quay | 16 | 5 | 5 | 6 | 14 | 17 | -3 | 20 |
| 4 | Cardiff MUCardiff MU | 12 | 3 | 6 | 3 | 12 | 17 | -5 | 15 |
| 5 | Pen-y-BontPen-y-Bont | 16 | 3 | 6 | 7 | 20 | 28 | -8 | 15 |
| 6 | Haverfordwest CountyHaverfordwest | 13 | 2 | 4 | 7 | 11 | 22 | -11 | 10 |
Bottom Six
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Caernarfon TownCaernarfon | 16 | 9 | 3 | 4 | 34 | 23 | 11 | 30 |
| 2 | Bala TownBala Town | 13 | 8 | 5 | 0 | 29 | 16 | 13 | 29 |
| 3 | Aberystwyth TownAberystwyth | 15 | 6 | 4 | 5 | 27 | 17 | 10 | 22 |
| 4 | Flint Town UnitedFlint Town | 13 | 6 | 1 | 6 | 23 | 21 | 2 | 19 |
| 5 | Barry Town UnitedBarry | 15 | 4 | 4 | 7 | 18 | 19 | -1 | 16 |
| 6 | Druids | 16 | 1 | 3 | 12 | 11 | 46 | -35 | 6 |
