Vizela vs. Boavista (Saturday, 3.30pm)
Meanwhile, a rampant Boavista side will be seeking their third win on the bounce following a 2-0 victory over Santa Clara on Monday.
We say: Vizela 1-2 Boavista
Vizela failed to build on their victory over Tondela as they came crashing back down to earth in a 4-0 loss to Vitoria, and next up for them is a Boavista side who appear to have already found their rhythm.
Boavista's defensive solidity has played a major role in their impressive start to the season and we predict they will keep the juggernaut rolling by claiming a narrow win on Saturday.
Porto vs. Arouca (Saturday, 6.00pm)
The visitors picked up their first win of the season last time out when they beat Famalicao 2-1 on home turf and will aim to build on that performance.
We say: Porto 3-0 Arouca
Fresh off the back of picking up their first win of the campaign, Arouca will head into the game feeling positive. While they will look to cause an upset, we are tipping Porto to claim a comfortable win as they boast a significantly stronger and more experienced crop of players.
Considering Arouca's struggles in front of goal, we also predict the hosts will come away with a clean sheet.
Famalicao vs. Sporting Lisbon (Saturday, 8.30pm)
Two teams who have had contrasting starts to the league campaign go toe-to-toe on Saturday when Famalicao welcome Sporting Lisbon to the Estadio Municipal de Famalicao.
The hosts were condemned to their third consecutive defeat last Friday, while the visitors made it three wins on the bounce with a 2-0 victory over Belenenses.
We say: Famalicao 1-2 Sporting Lisbon
Famalicao's defensive struggles have seen them fail to pick up a point from their opening three encounters. While they will be looking to end this poor run of results, they go up against a rampant Sporting Lisbon side, who have picked up seven wins in each of their last seven games across all competitions.
Given the difference in their current form, we are tipping Amorim's men to claim all three points and end their four-game winless run against the hosts.