Sittard vs. Groningen (Saturday, 5.45pm)
The hosts now sit in the automatic drop zone, having lost their last three games, while a win last time out lifted the visitors to 14th, five points better off than their opponents.
We say: Fortuna Sittard 0-1 Groningen
Given the hosts' struggles and Groningen's improvements recently, we predict a narrow away win on Saturday.
Fortuna should certainly not roll over in a game that they will view as a good opportunity to pick up points, but Ultee's men will be wounded by consecutive heavy defeats and may not have enough to avoid another loss.
PEC Zwolle vs. RKC Waalwijk (Saturday, 7.00pm)
The hosts currently sit at the foot of the division with just four points from the opening 13 games, while the visitors occupy 15th spot, just one point above the bottom three.
We say: PEC Zwolle 1-1 RKC Waalwijk
In a battle between two struggling sides desperate for a result, we see a cagey encounter taking place in Zwolle and cannot quite pick a winner.
Schreuder will hope to earn a positive result in his second game at the helm, but he may have to settle for a point against a side equally keen to improve their position at the bottom end of the table.
Willem II vs. Go Ahead Eagles (Saturday, 8.00pm)
However, the visitors have collected eight more points than their hosts from their last six outings, making them the marginal favourites to move past their ninth-placed opponents.
We say: Willem II 1-1 Go Ahead Eagles
With both teams sitting in relatively close proximity to the top four, they will feel that this is an opportunity to improve their season. However, that could lead to the sides cancelling each other out, resulting in a low-scoring draw.