There was some concern over Maxwel Cornet, who was forced off in the dying seconds of last weekend's draw with Reims, but the left-back has seemingly shaken off that problem and is in line to start over Mattia De Sciglio this weekend.
Anthony Lopes, Leo Dubois, Jason Denayer and Marcelo are all undroppable in the Gones rearguard, with the latter likely plying his trade in Lyon for one more year before his contract expires at the end of the season.
Thiago Mendes and Lucas Paqueta have also established themselves as integral cogs in Garcia's midfield, but the final spot in the engine room is up for grabs after Houssem Aouar's underwhelming first-half cameo against Reims and subsequent muscle injury.
Seventeen-year-old Rayan Cherki was also hauled off at half time against Reims for Tino Kadewere - who rescued a point in the last minute of the game - and the Zimbabwe international should take his rightful place alongside Memphis Depay and Karl Toko Ekambi in attack.
Garcia's front three have scored 36 of Lyon's 57 league goals this term, and each member of the trio will need to lace up their best shooting boots if they are to break down a resilient PSG rearguard.
Lyon possible starting lineup:
Lopes; Dubois, Denayer, Marcelo, Cornet; Mendes, Caqueret, Paqueta; Kadewere, Depay, Toko Ekambi