B. Leverkusen vs. Schalke (Saturday, 2.30pm)
Schalke, meanwhile, have scored only one goal in their last seven matches as they edge closer to their inevitable relegation.
We say: Bayer Leverkusen 3-1 Schalke 04
We expect Wolf to have an instant impact in his new role at Leverkusen by gaining a comfortable victory against a dismal Schalke side.
With Harit and Hoppe combining in attack, though, it would be no surprise to see Schalke end their woes in front of goal against a leaky Leverkusen defence.
Wolfsburg vs. FC Koln (Saturday, 2.30pm)
The Wolves, meanwhile, have opened up an eight-point gap inside the Champions League qualification positions, so will be looking to continue their momentum in terms of achieving their main objective.
We say: Wolfsburg 2-0 FC Koln
We expect Wolfsburg to be able to keep a Koln side lacking firepower at arm's length, with the Bundesliga's second strongest defence holding firm once again.
With Weghorst in attack, the Wolves always feel capable of scoring at least once in every match at the moment, which could prove enough to claim a crucial victory.
Augsburg vs. Hoffenheim (Saturday, 2.30pm)
The clubs are currently separated by just a point in the standings, with Hoffenheim in 11th on 30 points and Augsburg in 13th on 29.
We say: Augsburg 2-2 Hoffenheim
Hoffenheim look to be the stronger side, but their matches have been notoriously hard to predict this season due to their inconsistent nature. Augsburg need a result, and with both sides leaking goals, we think that this one will be a high-scoring draw.
Dortmund vs. Frankfurt (Saturday, 2.30pm)
Frankfurt hold a four-point lead over Dortmund in the table, so may view avoiding defeat as a positive step in terms of qualifying for the Champions League for the first time in the club's history.
We say: Borussia Dortmund 2-2 Eintracht Frankfurt
With both sides far more comfortable attacking than they are defending, it is hard to envisage a low-scoring encounter between these teams.
A draw would suit Frankfurt in terms of maintaining their four-point lead over Dortmund, and we think they have enough about them to get it.
Mainz 05 vs. Arminia Bielefeld (Saturday, 2.30pm)
Mainz are currently in 15th position, one point clear of the relegation playoff spot and two points ahead of Bielefeld, who are in 17th.
We say: Mainz 05 2-1 Arminia Bielefeld
Both teams will fancy their chances of winning this one, but we are backing Mainz to get all three points. There has been a real resurgence on the Rhine since the arrival of Svensson, Da Costa and Kohr in January, and we think that their winning run will continue against a Bielefeld side that lack matchwinners.
RB Leipzig vs. Bayern (Saturday, 5.30pm)
Bayern currently have a four-point lead ahead of Leipzig, so may view avoiding defeat as a huge step towards claiming their ninth successive title.
We say: RB Leipzig 1-1 Bayern Munich
With both sides potentially starting without a recognised striker, it is tough to envisage as many goals as in the reverse fixture, especially with the amount at stake for both teams.
While the onus is more on Leipzig to win the match, they have only beaten Bayern once in 11 meetings, so may find the psychological hurdle too high to scale even without Lewandowski on the pitch.
Borussia M'bach vs. Freiburg (Saturday, 7.30pm)
The visitors have overperformed their expectations this season, currently occupying eighth place as they look to finish in the top half of Germany's top flight for the fifth time this century.
We say: Borussia Monchengladbach 1-1 Freiburg
We expect Gladbach to have gained some confidence by ending their losing run against Schalke last time out, but it may not prove enough to beat a stubborn Freiburg side.
It is likely to be an evenly-contested game; Gladbach clearly have more attacking firepower, but Freiburg are slick in transition and have the tools to hurt the hosts.