Hoffenheim vs. Schalke (Saturday, 2.30pm)
Schalke, meanwhile, simply have pride to play for having already been relegated.
We say: Hoffenheim 3-1 Schalke 04
We expect Hoffenheim to put any lingering relegation concerns to bed with a win, although it may not come as easily as expected.
Both sides are missing several key defenders through injury and suspension, so the array of talented attackers on the pitch may well enjoy themselves.
Wolfsburg vs. Union Berlin (Saturday, 2.30pm)
Union Berlin, meanwhile, still have a chance of competing in Europe themselves next season.
We say: Wolfsburg 2-1 Union Berlin
We can envisage a narrow victory for the Wolves against a Union Berlin side which has proved tough to beat this season.
Glasner will be hoping Kruse does miss out with injury, as the visitors often lack creativity without their attacking talisman.
Werder Bremen vs. B. Leverkusen (Saturday, 2.30pm)
Leverkusen, meanwhile, are looking to cement their Europa League qualification spot.
We say: Werder Bremen 1-3 Bayer Leverkusen
Leverkusen seem to be in a good moment right now, and as such should have too much attacking firepower for Bremen to be able to handle.
The visitors may have to remain patient as, even during their recent losing run, Kohfeldt's side are often tough to break down in the early exchanges, so the first goal in this match will almost certainly be a crucial one.
Dortmund vs. RB Leipzig (Saturday, 2.30pm)
Both sides still have plenty left to play for in the league, however, with Dortmund chasing a Champions League qualification spot and Leipzig still mathematically able to overtake league leaders Bayern Munich.
We say: Borussia Dortmund 2-1 RB Leipzig
Dortmund's need for a win is arguably greater than Leipzig's, who may be more focused on Thursday's DFB-Pokal final.
Haaland and Sancho caused Nagelsmann's side major problems in transition in the reverse fixture, so if they are allowed similar amounts of space to run into, there is little doubting their decisive quality.
Bayern vs. Borussia M'bach (Saturday, 5.30pm)
Bayern Munich take on Borussia Monchengladbach in the Bundesliga on Saturday, with the hosts looking to seal a ninth successive Bundesliga title with a victory.
Gladbach, meanwhile, are aiming to secure European football for their incoming boss Adi Hutter to compete in.
We say: Bayern Munich 3-2 Borussia Monchengladbach
We can envisage a highly entertaining affair between two sides who have been scoring goals for fun in recent times.
Bayern will want to end their wait for a ninth successive league title after the disappointing loss to Mainz last time out, but equally Gladbach will not want to miss out on a European qualification spot this season.