Wins over Crystal Palace and Leicester City have lifted Paul Lambert's side to 11th and they will go above Liverpool and Tottenham Hotspur with another victory.
Six straight defeats during a nine-match winless run had seen the Villans drop towards the relegation zone, but they are now seven points clear of the bottom three.
West Brom find themselves in an almost identical position to where Villa were a few weeks ago - on an alarming slide down the table and desperately short of goals.
A 0-0 draw at fellow strugglers Hull City ended their four-match losing streak, but that stalemate marked the fourth time in five matches that Albion failed to find the net.
The England Under-21 star has been linked with a January move to either Liverpool or Spurs, but Irvine has insisted that he is not unsettled and will be staying put.
Captain Chris Brunt is a major doubt for the Baggies with a hamstring strain and so Porto loanee Silvestre Varela could make a full debut, having made several substitute cameos since recovering from groin surgery.
Jonas Olsson and Georgios Samaras are missing through injury, while Claudio Yacob is back from suspension, but unlikely to start in a home midfield which is likely to include former Villa man Craig Gardner.
Lambert revealed that key duo Ron Vlaar and Fabian Delph are back in full training, and the latter could be fast-tracked back into the starting lineup, with Ashley Westwood out and Tom Cleverley unlikely to feature.
Villa are also missing Philippe Senderos, Libor Kozak, Joe Cole and Nathan Baker, which means that Clark and Jores Okore should continue the young centre-back partnership that has performed well in recent weeks.
Andreas Weimann is available again after serving a one-match ban and should return on the wing at the expense of Charles N'Zogbia. The versatile Kieran Richardson may be asked to play in an injury-hit midfield.
Four of the last five meetings between these sides have been draw, and contained 17 goals in total.
Recent form: WLLLLD
Possible starting lineup: Foster; Wisdom, McAuley, Lescott, Pocognoli; Dorrans, Gardner, Morrison, Varela; Sessegnon, Berahino
Recent form: LDDDWW
Possible starting lineup: Guzan; Hutton, Okore, Clark, Cissokho; Delph, Sanchez, Richardson; Weimann, Benteke, Agbonlahor
Sports Mole says: 1-0