The Toffees are without victory against the Gunners in North London in 24 attempts and have avoided defeat in just four of those matches.
Ahead of Sunday afternoon's showdown with Arsenal, Sports Mole looks at how the visitors could line up.
No Premier League side has more players out injured than Everton, with the Toffees making the trip to the capital without seven senior players, the majority of whom would be considered for selection had they been fit.
There is one big positive for Silva, though, as Richarlison is back available after serving a three-match domestic ban for his red card against Bournemouth, meaning that Dominic Calvert-Lewin will almost certainly drop down to the bench.
The absence of Coleman at right-back gives Jonjoe Kenny a run in the side, and the academy product did not exactly disappoint in the loss to West Ham United last time out, while on the opposite flank Lucas Digne has usurped Leighton Baines.
Further forward, Theo Walcott will be looking to build on a tally of two goals and one assist in his first five Prem outings when he returns to his former club.