Arsenal head coach Mikel Arteta will likely field a makeshift starting XI for Saturday's FA Cup quarter-final with Southampton at St Mary's.
The Gunners saw a grand total of 10 players withdraw from international duty in March, as Eberechi Eze, Noni Madueke, Bukayo Saka, Declan Rice, Leandro Trossard, William Saliba, Gabriel Magalhaes, Jurrien Timber, Piero Hincapie and Martin Zubimendi were all sent home.
Eze and Madueke's issues will be serious enough to keep them out of this contest alongside Martin Odegaard (knee) and Mikel Merino (foot), and the same will likely be said for Ecuador's Hincapie.
All other Arsenal injury victims are on the touch-and-go list at present, but with the first leg of a Champions League quarter-final with Sporting Lisbon to factor into the equation, none should be risked if Arteta can help it.
As a result, expect several starters from the 2-1 win at Mansfield Town in the fifth round to reprise their roles here, include teenage starlets Marli Salmon and Max Dowman.
The latter could comprise a new-look attacker with Sweden World Cup hero Viktor Gyokeres and Gabriel Jesus, whose compatriot Gabriel Martinelli could be spared after his exploits with Brazil in the USA.
Myles Lewis-Skelly was banned for the Mansfield success but could now finally be trialled in a midfield role, occupying the left eight slot while Kai Havertz and Christian Norgaard accompany him.
Lewis-Skelly will have licence to operate in midfield if Riccardo Calafiori is fit enough to start at left-back, while Ben White, Cristhian Mosquera and Kepa Arrizabalaga should complete the backline.
Arsenal possible starting lineup:
Kepa; White, Salmon, Mosquera, Calafiori; Havertz, Norgaard, Lewis-Skelly; Dowman, Gyokeres, Jesus