Emmen vs. Heracles (Sunday, 11.15am)
On the flip side, Heracles are five points away from the last European playoff place, and any dropped points from here on could signal the end of their continental aspirations.
We say: Emmen 2-1 Heracles
The home side are full of confidence at the moment due to a strong run of form in the last eight weeks. We expect them to be pushed all the way in this one but nonetheless, we are backing them to get the job done.
Ajax vs. AZ (Sunday, 1.30pm)
However, if third-placed AZ prevail at the Johan Cruyff Arena, the lead at the top of the standings will be cut to nine points with four matches remaining.
We say: Ajax 2-1 AZ Alkmaar
After their disappointing result in midweek, we expect Ajax to come out firing on all cylinders. While AZ will make things difficult for the home side, Ten Hag's men could edge their way to victory, potentially with a late goal.
ADO Den Haag vs. Sittard (Sunday, 1.30pm)
Meanwhile, the visitors are going through a rough patch of their own having lost each of their last three games, scoring just one goal in that time.
We say: ADO Den Haag 1-2 Fortuna Sittard
Both sides have an opportunity to bounce back from disappointing results of late with a victory in this one. The away side are superior on paper, and we are backing them to show that supremacy on the pitch by claiming all three points.
FC Twente vs. Utrecht (Sunday, 3.45pm)
The away side are unbeaten in their last six games on the road, and they will aim to extend that run in order to keep up with their rivals in the race for European qualification.
We say: FC Twente 1-3 FC Utrecht
Both sides are still in with a shout in the race to secure continental football for next season, so nothing but three points will do for either team. The visitors come into this one in better form, and we are tipping them to carry the day.
Feyenoord vs. Vitesse (Sunday, 3.45pm)
De Stadionclub came back to beat Utrecht 2-1 in their previous match, while Ajax scored in injury time last weekend to deny Vitesse a chance to win their second Dutch Cup.
We say: Feyenoord 1-1 Vitesse
These are two evenly-matched teams separated by two points in the standings, while Vitesse have conceded one goal fewer than their opponents.
In the last four meetings between these sides, they are dead even with each team winning once, while the other two matches were draws.