It has been reported that the Polish attacker may spend some time away from Molineux on loan after spending over a year on the sidelines with a serious knee injury.
Zyro has previously spoken of his desire to break back into the first-team squad at the Championship outfit, but Nuno has hinted that a loan deal is under consideration.
The 43-year-old is quoted by the Express & Star as saying: "It depends on the conditions. First of all from my point of view we have to look at and respect the player. And what he's feeling also, and his will.
"If we found all the parts of happy and it's good for him he'll go and do it. Michal Zyro, everybody knows what he's been through in the last 18 months.
"He's coming from a very difficult injury and recovering well – and he needs to play. He knows that, we know that. We're going to find the best way to do it."
The 24-year-old has made just eight appearances for Wolves since signing for the club in January 2016.