Spurs sit fifth in the table ahead of this afternoon's kickoffs, having lost just twice so far this season.
The Hull City manager told Sky Sports News: "They're certainly a challenger. Spurs are now one of the big teams in the division as far as I'm concerned.
"Whether they are good enough to win it, that's a big call for them because they've got to beat Chelsea, Manchester City, Manchester United, Arsenal, but they've got a chance. In my opinion, they must have.
"You can only applaud what they've done. They lost Gareth Bale, a wonderful footballer, but as a squad and as a team there's an argument they're even better. They've got better players than us, let's be honest. They've assembled a really good squad over the years but that's not to say we can't go there and get a result."
Tottenham play Bruce's side tomorrow.