However, the North London outfit have an opportunity to inflict a blow on Everton's hopes of European qualification ahead of the remaining six fixtures of the season.
Here, Sports Mole rounds up all of Tottenham's latest injury and suspension news ahead of the contest at Goodison Park.
Type of injury: Calf
Possible return date: April 21 (vs. Southampton)
Having picked up a calf injury while on international duty with Wales, Davies has struggled to shake off the issue. Mourinho has previously suggested that the left-back is unlikely to come back in contention in the short term.
Type of injury: Muscle
Possible return date: Unknown
Mourinho took a similar view with the fitness of Doherty, who also sustained an injury while representing his country. The Irishman is expected to remain on the sidelines for this match.
TOTTENHAM'S SUSPENSION LIST
Tottenham have no players suspended for this encounter.