Reeling from a gut-wrenching UEFA Super Cup loss to Paris Saint-Germain, Tottenham Hotspur's Premier League campaign begins with a home tie against newly-promoted Burnley on Saturday.
The Lilywhites were on the verge of more continental stardom when they took a 2-0 lead in Wednesday's game, only for the Champions League holders to launch a tremendous comeback and complete the job on penalties.
Thomas Frank and co have little time to dwell on their European heartache, though, as Spurs prepare for a reunion with erstwhile midfielder Scott Parker, who led Burnley to a century of Championship points last season.
Here, Sports Mole rounds up all of Spurs' latest injury and suspension news ahead of their clash with the Clarets.
James Maddison
Status: Out
Type of injury: ACL
Possible return date: Unknown
James Maddison has started his long road to recovery from the ACL injury he suffered in pre-season, and it will be many months before the Englishman will be fit for action again.
Dejan Kulusevski
Status: Out
Type of injury: Knee
Possible return date: September 13 (vs. West Ham United)
Frank is without his two chief playmakers at present, as Dejan Kulusevski is also struggling with a knee problem, although his is expected to settle down within the next few weeks.
Destiny Udogie
Status: Out
Type of injury: Knee
Possible return date: August 23 (vs. Manchester City)
Destiny Udogie was laid low by a knee injury in pre-season, and while he is getting closer to returning to full training, the Italy left-back is not expected to be ready for the first Premier League game of the season.
Kota Takai
Status: Out
Type of injury: Foot
Possible return date: Unknown
New signing Kota Takai picked up a foot problem during the latter stages of July, and Frank has conceded that the Japanese defender will be absent for a matter of weeks.
Radu Dragusin
Status: Out
Type of injury: Knee
Possible return date: Unknown
Maddison is joined on the ACL treatment table by Radu Dragusin, who suffered his serious tear in January and is aiming to return before 2026.
Bryan Gil
Status: Out
Type of injury: Knee
Possible return date: Unknown
Spanish winger Bryan Gil suffered a knee injury while on loan at Girona last season, but the former Sevilla man is only on the fringes of the Spurs side anyway.
Manor Solomon
Status: Out
Type of injury: Calf
Possible return date: Unknown
Likewise, Manor Solomon could be a candidate for the chop before the summer transfer window closes, but either way, he is nursing a calf injury and has no estimated comeback date at present.
TOTTENHAM'S SUSPENSION LIST
Tottenham have no players suspended for this match.