Only a miracle would see Roma make the top four before the end of the 2019-20 campaign, but Paulo Fonseca's side are currently fifth in the table as they bid to secure a return to European football.
Roma did not finish outside of the top three in Serie A between 2013 and 2018 but ended last season in sixth, meaning that fifth would be an improvement, even if they are still some way off a return to the Champions League.
The Yellow and Reds have actually lost 10 of their 33 league matches this season, but they have won each of their last three in Italy's top flight to open up a four-point advantage over sixth-placed Napoli.
Fonseca's side will enter this weekend's match off the back of a 2-1 win over Hellas Verona on Wednesday night, while they have also beaten Parma and Brescia since losing at Napoli on July 5.
Inter, meanwhile, will enter Sunday's clash off the back of a 4-0 win over SPAL on Thursday night, which made it back-to-back successes in the league, having also beaten Torino earlier in the week.
Conte's side moved above Atalanta BC due to their success on Thursday and are now second in the table, six points behind leaders and reigning champions Juve.
A lot would have to happen over the next five matches for Inter to wrestle first position away from the Old Lady, but the Milan giants must keep winning and simply see where that takes them.
The Black and Blues are likely to fall short in terms of the title this season, but there is no question that they have made huge strides forward under Conte, and it could be a big summer window for the club.
Roma Serie A form: LLLWWW
Inter Milan Serie A form: WWLDWW
As for Inter, Romelu Lukaku was rested against SPAL on Thursday night, but the Belgium international is expected to return to the starting XI for this match.
Roma possible starting lineup:
Lopez; Mancini, Ibanez, Kolarov; Spinazzola, Zaniolo, Veretout, Zappacosta; Mkhitaryan, Dzeko, Pellegrini
Inter Milan possible starting lineup:
Handanovic; Skriniar, De Vrij, Godin; Young, Gagliardini, Brozovic, Candreva; Valero; Martinez, Lukaku
We say: Roma 1-1 Inter Milan
Inter are in need of a win to keep their slender title hopes alive, but Roma will be full of confidence following a run of three straight wins. We are struggling to pick a winner in this clash and have therefore tipped a low-scoring draw, which would be a good result for the home side.