McGeady notched two goals in the game, including a late winner with a fantastic strike from distance to get O'Neill's men off to a winning start in their campaign.
"He was the only player on the field that was scoring the goal. He really is a fantastic talent," O'Neill told Sky Sports News.
"He probably thinks at this age he should have been up there with the very finest players. He has that talent and he showed that tonight."
Ireland face Gibraltar in their next qualifying game on October 11.