The three-time Formula 1 champion believes that playing in the Champions League will financially help the club that he supports.
"I wish them all the best and hope they can finish fourth because then they'd have the chance to qualify for the Champions League, which would bring in extra revenue," he told Bundesliga.com. "That would obviously help a club like Frankfurt."
Vettel also explained how he became a Frankfurt supporter.
"It started because they're close to my home," said the 25-year-old. "Eintracht Frankfurt are the only Bundesliga club in [the state of] Hessen. That aside, they've been the most successful team in the region for years.
"Of course 1899 Hoffenheim are around now too, but Frankfurt were always the go-to club if you wanted to watch a Bundesliga match. That's how the connection with Eintracht started.
"Over the last few years I've got more and more interested in the Bundesliga, which is why I know my team a bit better."
Frankfurt will host Stuttgart in the Bundesliga on Sunday.