The Gareth Bale saga continues to develop in the Spanish capital, but Madrid have made a positive start to the campaign with back-to-back wins over Real Betis and Granada last time out.
Bilbao, now under the stewardship of Ernesto Valverde, have also been in impressive form, however, with victories over Real Valladolid and Osasuna giving them six points after the same number of games.
They have not enjoyed facing Madrid in recent seasons, however, losing each of their last five matches with the former Spanish champions, conceding 18 goals in the process.
Bilbao midfielder Ander Herrera has been the subject of a bid from Manchester United on Friday, but it appears that the Basque outfit are unwilling to sell the midfielder, meaning that he should start in the middle of their midfield.
Madrid: Lopez; Arbeloa, Pepe, Ramos, Marcelo; Modric, Isco, Ozil; Di Maria, Ronaldo, Benzema
Bilbao: Iago; Iraola, Laporte, Saborit, Gurpegui; Herrera, Benat, Iturraspe; Muniain, Aduriz, Sola
Sports Mole says: 3-1