The Royals currently occupy the final playoff spot, but are only in sixth on goal difference, and with a win would move above Wigan, three points ahead of them, in the hunt.
"We are looking forward to it, it's a very exciting end to the season," Sky Sports News quotes Adkins as saying. "Wigan are above us in the table, we can get closer to them with a victory or they can pull away from us.
"At this stage of the season the magnitude of results grows and grows and it's going to be a good one.
"Wigan have been magnificent - they've had a lot of games, the FA Cup semi-final and Europe. They want to get back up there at the first time of asking, but so do we."
The Latics also have a game in hand over Reading.