The 23-year-old suffered the injury on Saturday while on international duty with Nigeria.
Akpan, who has made 14 appearances for the Royals this season, is due to be back in action at the start of 2015.
Reading continue their Championship campaign on Friday when they make the trip to Cardiff City.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| C | Portsmouth | 44 | 27 | 13 | 4 | 75 | 39 | 36 | 94 |
| 2 | Derby CountyDerby | 44 | 26 | 8 | 10 | 75 | 37 | 38 | 86 |
| 3 | Bolton WanderersBolton | 44 | 24 | 11 | 9 | 81 | 48 | 33 | 83 |
| 4 | Peterborough UnitedPeterborough | 43 | 24 | 8 | 11 | 84 | 56 | 28 | 80 |
| 5 | Barnsley | 44 | 21 | 12 | 11 | 79 | 60 | 19 | 75 |
| 6 | Oxford UnitedOxford Utd | 44 | 21 | 10 | 13 | 76 | 54 | 22 | 73 |
| 7 | Lincoln CityLincoln | 44 | 19 | 14 | 11 | 63 | 37 | 26 | 71 |
| 8 | Blackpool | 44 | 20 | 10 | 14 | 60 | 43 | 17 | 70 |
| 9 | Stevenage | 44 | 18 | 13 | 13 | 54 | 44 | 10 | 67 |
| 10 | Leyton Orient | 44 | 17 | 11 | 16 | 50 | 53 | -3 | 62 |
| 11 | Northampton TownNorthampton | 44 | 17 | 8 | 19 | 55 | 63 | -8 | 59 |
| 12 | Wycombe WanderersWycombe | 43 | 15 | 13 | 15 | 55 | 53 | 2 | 58 |
| 13 | Exeter CityExeter | 44 | 16 | 10 | 18 | 43 | 58 | -15 | 58 |
| 14 | Bristol Rovers | 44 | 16 | 9 | 19 | 52 | 64 | -12 | 57 |
| 15 | Wigan AthleticWigan | 44 | 18 | 10 | 16 | 59 | 55 | 4 | 56 |
| 16 | Charlton AthleticCharlton | 44 | 11 | 19 | 14 | 63 | 63 | 0 | 52 |
| 17 | Reading | 44 | 15 | 11 | 18 | 63 | 65 | -2 | 50 |
| 18 | Shrewsbury TownShrewsbury | 44 | 13 | 8 | 23 | 33 | 63 | -30 | 47 |
| 19 | Cambridge UnitedCambridge | 43 | 12 | 10 | 21 | 38 | 59 | -21 | 46 |
| 20 | Burton Albion | 44 | 11 | 10 | 23 | 36 | 62 | -26 | 43 |
| 21 | Cheltenham TownCheltenham | 43 | 11 | 8 | 24 | 37 | 61 | -24 | 41 |
| 22 | Port Vale | 44 | 10 | 10 | 24 | 41 | 72 | -31 | 40 |
| 23 | Fleetwood TownFleetwood | 44 | 8 | 13 | 23 | 45 | 72 | -27 | 37 |
| R | Carlisle UnitedCarlisle | 44 | 7 | 9 | 28 | 40 | 76 | -36 | 30 |
| > League One Full Table | |||||||||
