The champions currently hold a six-point advantage at the top of the table, and a draw in their penultimate fixture would be enough to hold off the Lyon challenge.
Rolland Courbis will look at the final two games of the campaign as an opportunity to display just how far his Montpellier side have come in the space of a year since they struggled to a 15th-place finish last season.
It has been a much different season for Montpellier, and extra quality in certain areas could have been enough to earn them a place in the Europa League.
However, the club's supporters will be wary of expecting too much from this squad, and after improving so much in recent months, there is a renewed sense of optimism ahead of the summer transfer window.
Hopes of a top-six finish could be dashed before next week's meeting with Bordeaux, but Courbis is certain to see the match against the champions as a chance to cause an upset with a positive attacking performance in front of their home supporters.
Montpellier have lost just one of their last six home matches, and with only PSG, Lyon and Marseille winning more home games this season, the side should be full of confidence.
Recent form: DLWLDW
After spending much of the season battling Lyon and Marseille, before finally shaking off the latter, PSG are now on the brink of winning a third successive title thanks to Lyon's slip-ups in recent weeks.
In truth, Lyon may have done enough to win the title in previous years, but PSG have done brilliantly to capitalise on their failures and Laurent Blanc appears to have relieved the pressure which rested on his shoulders just a few months back.
An impressive Champions League campaign was halted by Barcelona, but the treble is still on for the club from the capital as they bid to add the Ligue 1 and Coupe de France titles to the Coupe de la Ligue success they enjoyed.
PSG have been simply unstoppable for much of the second half of the season, and their attacking talent has delivered the goods recently with 17 goals in the last four matches.
The summer transfer window is likely to be a busy one for the club as reports continue to link them with moves for Kevin De Bruyne, Yaya Toure and a number of other players, but it has been the likes of Edinson Cavani and Javier Pastore who have stepped up to prove their worth recently.
Avoiding defeat against Montpellier is certainly not the toughest challenge PSG have faced this season, but a loss would pile the pressure on once again ahead of the meeting with Reims on the final day of the season.
Recent form: WWWWWW
Recent form (all competitions): WLWWWW
Cavani and Ibrahimovic shared five goals in the emphatic win over Guingamp, and they should be joined by Pastore in a familiar attacking trio.
Montpellier possible starting lineup:
Ligali, Deplagne, Skhiri, El Kaoutari, Tiene, Saihi, Marveaux, Martin, Wuthrich, Mounier, Berigaud
PSG possible starting lineup:
Sirigu, Aurier, Maxwell, Silva, Marquinhos, Cabaye, Verratti, Matuidi, Pastore, Ibrahimovic, Cavani
Head To Head
PSG cruised to a 3-0 triumph when the two sides met in the Coupe de France in January, but Montpellier earned a point in the reverse league fixture when they held the champions to a goalless draw in the capital.
Montpellier have only won one of the last 12 matches between the two teams in all competitions, but there have been seven draws during that stretch of games.
PSG have not lost an away league fixture to Montpellier since suffering a 3-2 defeat in August 2003.
We say: Montpellier 1-3 PSG
Montpellier have been very impressive for long spells of the season, but they are likely to fall short in their bid for a top-six finish. PSG are in excellent form and they should clinch the title with a comfortable win.