Sittard, meanwhile, will be hoping to bounce back from their 1-0 defeat against Sparta Rotterdam, recording their eighth loss of the season.
PEC Zwolle currently sit in 12th place in the table, having picked up just three wins in their opening 16 matches.
However, it is worth noting that their home form has been fairly impressive this term, with John Stegeman's men unbeaten in their last five home matches, including an impressive 2-1 win against Vitesse last month.
If they manage a win this weekend, they could overtake both Heracles and Utrecht in the table, with the team still searching for their first victory of 2021.
On the other hand, Sittard were unfortunate to end their five-match unbeaten run on Wednesday, losing 1-0 to Sparta.
Besides their recent loss, Sittard appeared to be enduring a good spell of form - winning against Heerenveen, RKC Waalwijk and Heracles over the past month.
In fact, the visitors are unbeaten in their last three away games, with their latest away defeat coming against Vitesse in November.
They last met PEC Zwolle in that same month, with the result ending in a 2-2 draw between the two sides.
PEC Zwolle Eredivisie form: LDWDLW
PEC Zwolle form (all competitions): LDWDLL
Fortuna Sittard Eredivisie form: LWWDWW
PEC Zwolle will be without Slobodan Tedic for Saturday's clash, with the striker currently ruled out with a rib injury.
Meanwhile, Sittard fans will be pleased to know they have no injury concerns heading into this game, with Ultee able to choose from a fully fit squad.
The Dutch manager could also make a few changes to the starting XI that suffered a narrow defeat against Sparta, and he is expected to bring Mats Seuntjens back into the side.
PEC Zwolle possible starting lineup:
Zetterer; Van Wermeskerken, Kersten, Van Polen, Paal; Saymak, Strieder, Nakayama; Reijnders, Clement, Van Duinen
Fortuna Sittard possible starting lineup:
Van Osch; Rota, Angha, Janseen, Cox; Rienstra, Tekie, Flemming; Semedo, Polter, Seuntjens
We say: PEC Zwolle 1-1 Fortuna Sittard
Although PEC Zwolle are currently ahead of Sittard in the table, the visitors have been in superb form recently, and will hope to at least pick up a point when they travel to Zwolle this Saturday.