Les Aiglons suffered a 4-1 home defeat to Lyon at the weekend, whereas Lorient also lost on their own patch as Rennes cruised to a 3-0 win last time out.
Adrian Ursea's Nice were on a high after winning their first match of their new manager's reign, with Les Aiglons prevailing 2-0 at Nimes before welcoming Lyon to the Allianz Riviera.
However, the title-challenging Gones soon crashed the Nice party with a resounding 4-1 victory on Saturday evening, with Memphis Depay, Houssem Aouar, Karl Toko Ekambi and Tino Kadewere all on target while Amine Gouiri pulled one back for Les Aiglons.
The Nice faithful were certainly not expecting Ursea to turn their side into world-beaters from the off, but that defeat to Lyon means that Les Aiglons remain in the bottom half of the table in 13th - nine points clear of the drop zone as things stand - although Ursea's men do have a game in hand on all the teams below them.
Under Ursea and Patrick Vieira, Nice have now succumbed to defeat in their last six home games in all competitions, but the visit of a struggling Lorient outfit represents the perfect opportunity for the hosts to return to winning ways on their own patch.
Lorient's defeat to Rennes was overshadowed by a harrowing incident after the game in which a groundsman sadly lost his life after a heating structure collapsed and fell on him at the Stade du Moustoir.
Before that tragic accident, Lorient failed to get the better of Rennes as the European hopefuls eased to a 3-0 victory on the night courtesy of goals from Benjamin Bourigeaud, Damien Da Silva and Martin Terrier.
Les Merlus have now come up short in six of their last seven matches in the French top flight and are already being tipped to make an immediate return to the second division, with Christophe Pelissier's side in 19th heading into Christmas.
Lorient are three points adrift of safety as things stand, but even if Pelissier's men somehow come up trumps in this game, Les Merlus are highly unlikely to climb out of the danger zone with Strasbourg and Reims boasting a far superior goal difference.
While Nice have struggled for results at home recently, Lorient have only taken four points on the road all season, and Les Merlus have managed to pick up a solitary win in their last seven meetings with Nice.
Nice Ligue 1 form: LLDLWL
Nice form (all competitions): LDLLWL
Lorient Ligue 1 form: LLLWLL
Nice's Morgan Schneiderlin will return from a suspension for this one, but Saturday's goalscorer Gouiri serves a ban of his own for the visit of Lorient.
The loss of Gouiri leaves Ursea with a huge call to make up top as Kasper Dolberg has been ruled out of action until the New Year, while Les Aiglons' other centre-forward Myziane Maolida is nursing a thigh problem.
However, Ursea will be boosted by the return of Jeff Reine-Adelaide, who was ineligible to face his parent club Lyon, and the Frenchman could line up on the left-hand side of the attack with Dan Ndoye leading the line.
Nice possible starting lineup:
Benitez; Pelmard, Bambu, Nsoki; Atal, Schneiderlin, Boudaoui, Kamara; Lopes, Ndoye, Reine-Adelaide
Lorient possible starting lineup:
Nardi; Delaplace, Laporte, Morel, Le Goff; Chalobah, Lemoine; Diarra, Boisgard, Wissa; Grbic
We say: Nice 1-0 Lorient
Both of these teams will be desperate to round off the year on a high note after a challenging start to the campaign, and Lorient may feel cautiously optimistic given Nice's worrying home form. However, Ursea's men should still have too much quality for the relegation candidates, even without a recognised striker, so we expect Les Aiglons to take the spoils in this one.