Davide Santon has been handed his first start for Inter Milan since rejoining the club from Newcastle United on deadline day, filling in at full-back for tonight's Coppa Italia clash against Napoli.

There is also a first Nerazzurri start for Marcelo Brozovic for the Stadio San Paolo showdown, while Daniel Osvaldo remains frozen out for a visiting side looking to keep their cup ambitions on track following what has been a disappointing league campaign to date.

As far as the hosts are concerned, Faouzi Ghoulam is back among the squad having returned from Africa Cup of Nations duty, but somewhat surprisingly Kalidou Koulibaly has been named at right-back.

Further forward, Gonzalo Higuain leads the line with Marek Hamsik, Jonathan de Guzman and Jose Callejon providing additional attacking impetus.

Napoli: Andujar; Koulibaly, Albiol, Britos, Strinic; Gargano, David Lopez; Callejon, Hamsik, De Guzman; Higuain
Subs: Rafael, Colombo, Jorginho, Maggio, Mertens, Gabbiadini, Ghoulam, Uvini, Inler, Duvan Zapata

Inter Milan: Carrizo; Nagatomo, Ranocchia, Juan Jesus, Santon; Brozovic, Medel, Hernanes; Shaqiri; Icardi, Puscas
Subs: Handanovic, Berni, Palacio, Kovacic, Podolski, Guarin, Vidic, Kuzmanovic, Obi, Dodo, Donkor