The home side head into this match sitting just outside the top half of the table, whereas the visitors are currently in the European places.
Moreirense have endured a mixed start to the 2020-21 season, winning just three of their opening 12 league games, including only one of their last seven.
Just as they have a shortage of wins, the same could be said of their goalscoring exploits. They are the second-lowest scorers in the league having netted just three goals in their last seven league matches and, in doing so, drawing blanks on four occasions.
When it comes to their previous meetings with the opposition, they have also struggled with only one victory in their last six meetings, the most recent of which ended in a 1-1 draw.
The visitors gave a better account of themselves in their previous match but still suffered a narrow 3-2 defeat; the manner in which they played, however, will give them a further confidence boost.
Their fourth defeat of the season left the away side in fifth position and increased the pressure to hold onto the last European place, with Pacos de Ferreira now level on points.
However, Vitoria do now boast a game in hand over the teams around them in the table due to their last match being postponed, and victory on Saturday could close the gap on fourth-placed Braga to only a single point.
Despite the minor blip, they have been in great form having racked up an impressive six victories in their last nine league matches.
Just as they have been impressive going forward, at the back they have been equally as good, boasting the third-best defensive record in the league.
Moreirense Primeira Liga form: LLDDWL
Moreirense form (all competitions): LDWDWL
Vitoria de Guimaraes Primeira Liga form: WLWWWL
Vitoria de Guimaraes form (all competitions): WWWLWL
The hosts could line up in a 5-4-1 formation.
The away side could start in a 4-3-3.
Moreirense possible starting lineup:
Pasinato; Figueiredo, Vitoria, Pacheco, Rosic, D'Alberto; Pires, Soares, Soares, Yan; Santos
Vitoria de Guimaraes possible starting lineup:
Varela; Mensah, Mumin, Fernandes, Sacko; Andre, Pepelu, Almeida; Rochinha, Estupinan, Quaresma
We say: Moreirense 1-2 Vitoria de Guimaraes
We expect this to be a close contest, but Vitoria de Guimaraes should come out as victors.
Moreirense have struggled to win of late in the league, and the visitors should have too much for them. Vitoria de Guimaraes are in great form and they should walk away with all three points.