Middlesbrough play host to Preston North End on Tuesday night looking for the victory which could move them back into the top half of the Championship standings.
However, should 16th-placed Preston prevail at the Riverside Stadium, they will progress a point ahead of their North-East hosts.
Match preview
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As opening games go for your first match at a new club, Chris Wilder would have been delighted with a home fixture against Millwall, a team who also find themselves as outsiders for the playoffs.
The signs were there that Boro would record a win for the replacement for Neil Warnock, but Sol Bamba's own goal cancelled out Matt Crooks's earlier strike.
Boro have now gone four games without success, while the gap to sixth-placed Queens Park Rangers now stands at six points.
Nevertheless, Wilder was full of praise for his squad, acknowledging after the contest that he is trying to instill a new style of play.
While another game three days later will be tough on the legs, Wilder will recognise that Boro have a great opportunity to regain some momentum in the race for the playoffs.
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Frankie McAvoy will be of a similar opinion to his opposite number as Preston look to bounce back from successive defeats.
Preston were on a huge high when they stunned Bournemouth earlier this month, but back-to-back setbacks against Nottingham Forest and Cardiff City have left North End down in 16th spot.
Losing to the Bluebirds on Saturday was particularly frustrating after they had taken a second-minute lead, Sean Maguire finally registering his first league goal of the season.
That represented just their second home defeat in nine games, a record in sharp contrast to Preston collecting just six points from the same amount of fixtures on the road.
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Team News
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Having felt that his players tired during the latter stages against Millwall, Wilder will consider making changes to his Middlesbrough XI.
Onel Hernandez is an option for the wing-back positions, while Neil Taylor may be given a chance after signing on a free transfer.
Uche Ikpeazu and Josh Coburn are alternatives in the final third with Duncan Watmore most likely to drop out.
McAvoy will also likely make alterations to his Preston side with Josh Earl and Daniel Johnson both in contention for recalls.
Liam Lindsay, who has not played in the Championship since the start of October, will also hope for an opportunity in defence.
Middlesbrough possible starting lineup:
Daniels; McNair, Bamba, Peltier; Jones, Crooks, Howson, Tavernier, Bola; Sporar, Watmore
Preston North End possible starting lineup:
Iversen; Van den Berg, Bauer, Hughes; Barkhuizen, Ledson, McCann, Earl; Johnson; Maguire, Jakobsen
We say: Middlesbrough 2-1 Preston North End
With neither team being in great form, they will both be eager to use this game as the catalyst for greater things to come. While Preston still have the win at Bournemouth fresh in their memory, we expect Boro to edge this contest by the odd goal in three.
Top tip
Darren Plant
Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Middlesbrough win with a probability of 48.8%. A draw had a probability of 27.3% and a win for Preston North End had a probability of 23.86%.
The most likely scoreline for a Middlesbrough win was 1-0 with a probability of 14.27%. The next most likely scorelines for that outcome were 2-0 (9.95%) and 2-1 (8.81%). The likeliest drawn scoreline was 1-1 (12.63%), while for a Preston North End win it was 0-1 (9.06%). The actual scoreline of 1-2 was predicted with a 5.6% likelihood.
