Man Utd vs. Sheff Utd (Wednesday, 6.00pm)
The Red Devils currently sit in fifth place following their draw with Tottenham Hotspur on Friday night, two points clear of Wednesday's opponents following the Blades' surprise 3-0 loss against Newcastle United.
We say: Man Utd 2-0 Sheffield United
Sunday's defeat to Newcastle was an anomaly for Sheffield United, but this always looked likely to be a difficult fixture for them regardless of what happened at St James' Park.
With the visitors' defensive absentees and Man United close to full strength, we are backing Solskjaer's side to pull off a crucial victory for their European hopes.
Newcastle vs. Aston Villa (Wednesday, 6.00pm)
Newcastle United welcome Aston Villa to St James' Park on Wednesday evening for their second behind-closed-doors home game in the space of three days.
The Magpies beat Sheffield United 3-0 in their first match back after lockdown on Sunday, whereas Aston Villa remain in trouble at the bottom of the table having taken only one point from their two games since returning.
We say: Newcastle 1-0 Aston Villa
If Newcastle's forwards have indeed found their shooting boots then Aston Villa's league-worst defence could struggle to keep them out, whereas the Magpies' recent defensive record at home is too good to ignore.
Aston Villa are in greater need of a victory but they are not quite in the last-chance saloon yet, so we are backing Bruce to get one over on his former club.
Norwich vs. Everton (Wednesday, 6.00pm)
We say: Norwich 0-2 Everton
Norwich appear to be slipping closer and closer to the exit door of the Premier League and, while Everton are also on a winless run of their own, they should enough quality to see the hosts off at Carrow Road.
Wolves vs. Bournemouth (Wednesday, 6.00pm)
Meanwhile, Bournemouth make the trip to the West Midlands having suffered four defeats in five matches, a run which has left the Cherries in the relegation zone.
We say: Wolverhampton Wanderers 3-1 Bournemouth
While Wolves impressed during their win over West Ham, they will be up against a Bournemouth outfit which can only improve after their dismal showing against Palace. Nevertheless, we expect Wolves to run out fairly-convincing winners on Wednesday night.
Liverpool vs. Crystal Palace (Wednesday, 8.15pm)
Liverpool could take another step towards a first title since 1990 when they welcome Crystal Palace to Anfield for their first behind-closed-doors home game since lockdown.
The Reds returned to action with a goalless draw against Everton at Goodison Park on Sunday to leave themselves five points away from glory, and take on a Palace side in flying form and with their sights set on European qualification.
We say: Liverpool 2-0 Crystal Palace
There is a perception that Palace are something of a bogey team for Liverpool, having inflicted the most recent Premier League defeat on them at Anfield and all but ended their title hopes in the 'Crystanbul' match of 2014.
However, Liverpool have won the last four meetings and six of the last seven, and we expect them to continue that run on their first game back at Anfield since March despite Palace's admirable form heading into the contest.