After they take on the Baggies, United face Premier League leaders Chelsea at Old Trafford and then make the short trip to rivals Manchester City.
Despite the magnitude of those games, Mata has claimed that everybody connected with the club is focused purely on getting a positive result at The Hawthorns.
"We only have to think about this game. The manager is only speaking about West Brom and that's the same for us," he told the club's official website.
United, who are sixth in the Premier League table, last lost away at West Brom back in 2003.