Braga suffered a 3-2 defeat to United two weeks ago and they are in desperate need of the three points with Cluj currently occupying second spot in the group.
United will wrap up progression if they can secure all three points against the Portuguese outfit and they enter the match off the back of an impressive performance against Arsenal.
Braga also enter the match with victory under their belt, however, and they will attempt to use home advantage to inspire them to victory over Sir Alex Ferguson's side.
Braga have no fresh injury concerns to contend with and are expected to name Alan and Eder in attack once more. Meanwhile, United could name the same side that started at the weekend, but Anderson is pushing for inclusion.
Manchester United: WWWLW
Braga: Beto; Douglao, Vinicius, Echiejile, Coelho; Amorim, Viana, Custodio, Salino; Alan, Eder
Manchester United: De Gea; Rafael, Ferdinand, Evans, Evra; Valencia, Carrick, Cleverley, Young; Rooney, Van Persie
Sports Mole says: 1-2