The Bianconeri are currently eight points clear at the top of the table and can take another big step towards the Scudetto with victory at the Stadio Olimpico.
Petkovic paid homage to his counterpart Antonio Conte, but does not believe that his team are unbeatable.
"It's true the Bianconeri are close to the Scudetto, but there is no such thing as an impossible game. Nobody is unbeatable, not even Juventus," Football Italia quotes Petkovic saying.
"We already put Juve under pressure and knocked them out of the Coppa Italia semi-final. We must never let up the intensity for the full 90 minutes and ensure we don't let them play at their best.
"I really admire Antonio Conte, as he is one of the best Italian coaches with such grit and determination."
The Biancocelesti won 2-1 in the Coppa Italia in January.